GOOD QUESTIONI have an example that i am currently mulling over in my brain:
I have a a poorly aspected Moon. No major aspects to personal planets except Jupiter and the orb is almost two wide to count (8 degrees).
Moon semi-sextile Sun (2 degrees)
Moon trine Saturn (1 degree)
Moon square Uranus (2 degrees)
Moon square Neptune (1 degree)
Moon conjunct Jupiter (8 degrees)
I recently met several men who's Sun is in close conjunction to my moon (the universe responds to me like this sometimes lol believe it or not) with one in particular who's Sun, Mercury, and Venus conjunct my moon. His mars also trined my moon and his own moon made a nice sextile as well.
He still rubs me the wrong way for some reason, but I still find myself wanting to communicate with him. I blame Moon-Saturn, Moon-Pluto.
So I guess my point is, sometimes the lack of aspects in our own chart might be EXACTLY what we need to feel emotionally safe and secure. It's like an oxymoron? You would think someone filling in all those "holes" WOULD fill us up, but sometimes those holes are there for a reason and don't need to be filled.
SideNote: I had a best friend in high school whose mercury and venus trined my moon and it waa one of the most fulfilling relationships I've ever had so who knows. I will continue to observe lol